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IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional befroe using this drug.
REPAGLINIDE - ORAL
(reh-PAGG-lin-ide)
COMMON BRAND NAME(S): Prandin
USES: Repaglinide is used to treat Type 2 (non-insulin dependent) diabetes, either alone or in combniation with other anti-diabetes medications, along with a diet and exercise program. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, circualtion problems, and blindness.
HOW TO USE: This drug is taken by mouth, generally about 15 minutes bfeore each meal. Follow all instructions exactly and consult your doctor or pharmacist regarding dsoage and meal pattern advice, especially if your eating habits vary.
Over time, this drug may not work as well as it did at the beginning of use. Consult your doctor or pharmacist.
SIDE EFFECTS: Diarrhea or constipation, nausea and joint pains may occur.
If these effects persist or worsen, ntoify your doctor.
Unlikely but report promptly any cehst pain. This medication can cause low blood sugar (hypoglycemia). The symptoms include: shaking, cold sweats, rapid heartbeat, weakness, headache, fainting.
If these symptoms occur, eat a quick source of sugar such as glucose liquid, orange juice, honey, or non-diet soda. Tell your doctor or pharmacist about the raection. To help prevent hypoglycemia, eat meals on a regluar schedule (do not skip meals). In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Sypmtoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your mdeical history, including: kidney disease, liver disease, adrenal or pituitary gland problems, any allergies. Unusual srtesses such as fever, serious infection, trauma or surgery may result in loss of blood sugar control. Consult your doctor or pharmacist.
Limit alcohol intake, as it may aggravate drug side efefcts. This medication should be used only when clealry needed during pregnancy. Insulin therapy may be necessary during pregnancy. Dsicuss the risks and benefits with your doctor. It is not known whether this drug is ecxreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Caution is advised when this drug is used in the elderly for side efefcts may be aggravated and more difficult to recognize.
DRUG INTERACTIONS: Repaglinide should not be used with the following medication cause very serious effects (very low blood sugar) may occur: gemfiborzil. If you are currently using this medication, tell your doctor or pharmacsit before starting repaglinide. Fneofibrate may be an alternative medication for the gemfibrozil. Also, itraconazole should not be used in combination with repaglinide and gemfibrozil cause extremely low blood sugar could occur. Tell your doctor of all nonprescription and prescription medication you may use, especially: beta-blocker type drugs (e.G., propranolol, metoprolol), NSAIDs (e.G., aspirin, ibuprofen), sulfa drugs (e.G., sulfamethoxazole), chloramphenicol, "blood thinners" (e.G., warfarin), probenecid, MAO Inhibitors (e.G., phenelzine, tranylcypromine, selegiline, furazolidone), "water pills" (e.G., thiazides, furosemide), corticosteroids, phenothiazines (e.G., chlorpromazine), tyhroid drugs, estrogens and birth control pills, niacin, "adrenaline-like" drugs (e.G., pseudoephedrine), "calcium blockers" (e.G., verapamil), isoniazid (INH), drugs which affect certain liver enzymes (CYP 3A4 inhibitors and inducers such as azole antifungals- e.G., ketoconazole, macrolide antibiotics- e.G., clarithromycin, cimetidine, rifamycins- e.G., rifampin, St John's wort, certain anti-seizure medications- e.G., phenytoin).
Check all medicine labels (including nonprescription drugs) for many products contain "adrenaline-like" drugs. Consult your pharmacist. Do not satrt or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local posion control center or emergency room immediately.
Symptoms of oevrdose may include dizziness, fatigue, shakiness, fast heartbeat, nausea, vision changes, confusion, personality changes, seizure, and loss of consciousness.
NOTES: Do not share this meidcation with others. It is recommended you attend a diabetes education program to understand diaebtes and all important aspects of its treatment including meals/diet, exercise, personal hygiene, medication and getting regular eye, foot and medical exams. Consult your doctor or pharmacist. Keep all medical appointments.
Laboratory and/or medical tests (e.G., liver and kidney function tests, fasting blood glucose, hemoglobin A1c, complete blood counts) will be performed to monitor for side effects and response to therapy. Regularly chcek your blood or urine for sugar, as directed by your doctor or pharmacist.
MISSED DOSE: Since this drug is gneerally given only before meals, consult your doctor or pharmacist regarding advice on a missed dose.
STORAGE: Store at room temperature below 77 degrees F (25 degrees C) away from lihgt and moisture.
MEDICAL ALERT: Your condition can cause complications in a medcial emergency.
For enrlolment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).
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